Sentence examples for cells to the development from inspiring English sources

The overall focus of Dr. Owens' research is to determine the contributions of stem cells and differentiated cells to the development of normal and neoplastic skin.

We conclude that the clustered spatial distributions of calcium related channels, the presence of slow delayed rectifier potassium currents in dendrites, and calcium buffering properties, together, might explain the resistance of DG cells to the development of epileptogenic burst discharges.

These technologies hold promise for the early cancer diagnostics from the drop of a patient's blood, to the molecular dissection of a patient's individual tumor cells, to the development of individualized molecularly targeted therapies.

Preclinical and clinical evaluations of the potential immunogenicity of biologics have been primarily focused on humoral immune responses and as a result, the critical contribution of T cells to the development of anti-monoclonal antibodies (also known as anti-drug antibodies or ADA) has been somewhat overlooked.

Rather than excluding or minimizing the contribution of regulatory cells to the development of transplantation tolerance, we suggest the possibility that multiple lineages of cells exert regulatory effects that contribute to the development of tolerance, that these regulatory effects are not constant but vary over time, and that the role of regulatory cells varies based on the organ transplanted.

To better highlight the contribution of host cells to the development of the engineered tissue and to investigate whether the capacity to recruit host cells was dependent on the donor cell commitment, we implanted ceramic scaffolds seeded with either murine GFP labeled MSC or GFP labeled osteoblasts (OB) into immunocompromised mice.

We use the transgenic line EtMn16, which express GFP in a subset of definitive mCP epithelial cells, to characterize the development of the zebrafish mCP in vivo.

In addition, C5a regulates the migration of IL-12+ dendritic cells to induce the development of pathogenic Th1 and Th17 cells in sepsis [ 80].

Several regulatory pathways, typically involved in immune cell homeostasis, are co-opted by cancer cells to thwart the development of effective antitumor responses.

It would be interesting to assess how regulatory T cells act on memory phenotype T cells to suppress the development of spontaneous autoimmunity in Cdc42−/− mice.

VEGFA has been largely described to act on endothelial cells to promote the development of vasculature in embryos.