Sentence examples for cells to malfunction from inspiring English sources

Instead, the scientists will use the cells to learn how genetic mutations cause heart cells to malfunction and ultimately cause life-threatening cardiomyopathy.

Michael Welsh led the team that made key discoveries toward elucidating the role of the product of this gene, the CFTR protein, as the chemical transporter that allows chloride to move in and out of cells, showing how mutations in the gene and its product cause cells to malfunction and fuel disease development.

The idea was to deliberately cause these cells to malfunction and then watch what happened.

So Mongkolsapaya, Gavin Screaton of the University of Oxford, and their colleagues asked whether dengue was also causing T cells, which ordinarily kill virus-infected cells, to malfunction.

Possible mechanisms for the failures include: the compound is not incorporated into cellular proteins, its incorporation causes one or more of the proteins in the cells to malfunction, or it interferes with some metabolic steps in the cells.

But little is known about what occurs when memory declines during normal aging, except that brain cells begin to malfunction, says Scott Small, a neurologist at Columbia University and senior author to the study.

And when they get too short, our cells start to malfunction and lose their ability to divide – a phenomenon that is now recognised as a key process in ageing.

When the telomeres become very short, the cell starts to malfunction and show signs of ageing.

Intracellular protein aggregates are formed when misfolded polypeptides accumulate in the cells due to malfunctioning or overloading of the protein quality control machinery or of the components of the degradative pathway [4].

This pump, critical for maintaining the integrity and function of brain cells, is vulnerable to malfunction under stress associated with conditions such as epilepsy and stroke, and others, including Alternating Hemiplegia of Childhood (AHC).

In 1989, Tsui teamed up with Francis Collins and his collaborators to publish a seminal trio of papers that pinpointed the exact location of the CFTR gene on chromosome 7 and defined the precise array of genetic mutations that cause the cells' chloride-transporting protein to malfunction.