Exact(1)
Whereas LTA did not induce any significant leukocyte adhesion (Fig. 6A) or emigration (Fig. 6B), the other TLR2 ligands that were tested: R-FSL1, S-FSL1, Pam2CSK4, and Pam3CSK4, each induced on average between 15 19 cells to adhere (Fig. 6A) within the venules and 30 70 cells to emigrate (Fig. 6B) into the tissue.
Similar(59)
Activated effector CD8+ T cells begin to emigrate from the DLN to the infected lungs on day 5 6 p.i. and continue to accumulate in the infected respiratory tract over the next 3 4 days [20].
Firstly, the tumor cells have to emigrate from the primary tumor and enter the site of dissemination, either hematogeneous or lymphogeneous, with the lymphogeneous route discussed to be a default pathway for tumors incapable of crossing blood vessel endothelia [ 10].
Endothelial cells need to loosen the interendothelial cell contacts to emigrate from their resident sites [ 40].
Cephalic NC cells are known to emigrate earlier than trunk NC in all species studied, including recently derived human NC cells [40].
In a real neoplasm, cells are likely to emigrate through lymphatic and blood vessels, not just by leaving the borders of the neoplasm.
To discriminate whether this effect is due to the duration of Notch activity or, alternatively, to a positional effect induced within the sclerotome on cells initially stimulated to emigrate by Notch, Notch was conditionally activated twenty hours post-EP for eight hours only followed by fixation.
These cells are also more likely to emigrate from the tumor, which is the first step in metastasis and the key to the puzzle of metastasis.
Bright CD3 expression is a hallmark of mature T cells which are either preparing to emigrate or are residing in the perivascular space of the thymus.
These data support our finding that cells in APC Min/+ tissue fail to emigrate efficiently from the crypt.
They seem to have wanted to emigrate.
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