Sentence examples for cells to alterations from inspiring English sources

Considering the specificity of the examined organelles, their sensitivity to environmental factors and dynamics, it can be assumed that these changes are an adaptive response of cells to alterations in their environment.

More recently, we linked the switch in TGFβ signaling pathways in HPV16-transformed cells to alterations of the expression of the homeobox transcription factor SIX1, linked to invasiveness and aggressive behavior in a variety of cancers, including cervical cancer [76],[76].

To create that model, Nelson must answer several basic questions about how fibrotic cells behave: How do cells respond to alterations in the stiffness of their surroundings?

Proteomic analysis was performed on the isolated alveolar type II cells to discover alterations in cellular pathways at the protein level that might contribute to injury.

During tubulogenesis such a material is normally secreted by the surrounding epithelial cells to coordinate alterations in shape resulting in a correct lumen dimension [ 19].

Notch signalling refers to a range of cell cell interactions where Notch ligands, such as the delta-like ligands (dll1-4) and jaggeds (jag1&2) interact with Notch receptors on neighbouring cells to induce alterations in gene expression and cellular phenotype.

Expression of transgenes incorporating the T/C variant GPX4 (rsequencessequences in Caco-2 cells leads to alterations in both cell viability after an oxidative challenge and selenoprotein expression.

Therefore, changes in gonadotropin levels or a direct effect of PBDE on granulosa cells, leading to alterations in FSH receptors on these cells, could affect follicular maturation.

Due to its importance in downstream T cell functions, we examined whether the hyperphosphorylation of PLC-γ1 in Jurkat E6.1 T cells lead to alterations in the levels of TCR-induced Ca2+ influx in the T cell lines and APBTs.

Association with the nuclear periphery (nuclear lamina) is known to be a characteristic of late replication timing6,9,26, however, it is less clear how differences in nuclear lamina association between normal and cancer cells relate to alterations in cancer-associated replication timing.

In this report, we demonstrate that genetic ablation of the Cby gene results in perturbed postnatal lung maturation with reduced proliferation and impaired differentiation of pulmonary epithelial cells, leading to alterations in the mechanical properties of the lungs.