Sentence examples for cells that succeed from inspiring English sources

The cells that succeed to escape the block and to differentiate into mature B cells have post-translationally downregulated the expression of transgene, indicating that expression of OBF1 beyond the normal level early in B cell development is deleterious.

Intracellular FACS analysis of the EPLM cultures indicated that the cells that succeed to upregulate CD19 also downregulate the OBF1 transgene (Fig. 3C), much like what had been observed in early B cells progressing through developmental stages in vivo.

Indeed, the cells that succeed to pass this developmental block downregulate the transgene post-translationally, indicating that the level of OBF1 has to be low at this stage for proper B cell differentiation.

Those breast cancer cells that succeed to colonize the lung are those which produce tenascin as a metastatic niche complement [ 202].

As metastatic cell clones represented only part of the primary tumor population [ 55], the cells that succeed engraftment in mice may actually represent one of the subpopulations of the primary tumor with higher metastatic potential.

Here, by examining the timing of NEBD relative to the onset of Eg5-mEGFP loading to centrosomes, we show that a time window of 9.2 ± 2.9 min is available for Eg5-driven prophase centrosome separation ahead of NEBD, and that those cells that succeed in separating their centrosomes within this window subsequently show >3-fold fewer chromosome segregation errors and a somewhat faster mitosis.

The number of bacterial cells that succeeded in infection was subsequently determined.

As quantified in Figure S2B, Myo19 cells that failed division in the first round could produce daughter cells that succeeded in the second, and vice versa.

That is, only vectors that succeed in cell entry and genome delivery generate a signal.

A Myo19 RNAi Cell That Succeeds in Cell Division Despite the Clumped and Asymmetric Mitochondria, Related to Figure 3 Time-lapse imaging as for Movie S1 of HeLa cells treated with siMyo19 and labeled with MitoTracker Green (grayscale signal) 48 hr posttransfection.

The existence of this time window for kinesin-5-driven centrosome separation suggested to us that cells race to complete centrosome separation ahead of NEBD, and that prophase pathway cells are those that succeed, whilst prometaphase pathway cells are those that fail.