Tumor spheroids are aggregates of cancer cells that preserve native 3D cell-cell contact, mimicking the configuration of solid tumors (Weiswald et al. 2015).
For example, tumours in Drosophila melanogaster only may arise before the larval stage, thus from cells that preserve a proliferating potential and as such are not terminally differentiated.
The developing and adult CNS (central nervous system) of higher vertebrates contains NPCs (neural progenitor cells) that preserve the capacity to self-renew throughout most of the adult life (Eriksson et al., 1998).
Efficient lentiviral transduction of human mesenchymal stem cells that preserves proliferation and differentiation capabilities.
Overstimulated Leydig cells as well as those cells that preserved their normal structure and function (seen in semithin sections) could produce enough testosterone to maintain the normal serum levels.
Now the basic feature a CA needs to perform computations is the capacity of its transition rule of producing "particle-like persistent propagating patterns" (Ilachinski 2001, p. 89), that is, localized, stable, but non-periodic configurations of groups of cells that can preserve their shape (sometimes called solitons in the literature).
We identified both low and high concentrations of TM (low, 1 μM, high, 100 μM), TG (low, 0.1 μM, high, 50 μM), and DTT (low, 1 mM, high, 10 mM) for HepG2 cells that could preserve and diminish cell viability, respectively.
We used flow cytometry to assess molecules on cells that were preserved during flight to define the differentiation state of the developing bone marrow macrophages; including CD11b, CD31, CD44, Ly6C, Ly6G, F4/80, Mac2, c-Fos as well as c-Fms.
They used several recently-developed techniques to study cells that were preserved in a close-to-living condition.
In an update of the embryonic theory of cancer, that suggested cancers arise from embryonic cells that are preserved in adult tissue, it has recently been popular to think that tumours have rare cells that retain stem cell like properties that can divide asymmetrically and retain a capacity for self-renewal.
To address this, we used immunoguided laser-capture microdissection to isolate prostate basal and luminal epithelial cells under conditions that preserve RNA of sufficient quality for expression profiling.
