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Taken together, these data show that mutant IDH or d-2HG causes persistence of chondrocytes, giving rise to rests of growth-plate cells that persist in the bone as enchondromas.
Previously activated regulatory T (TReg) cells that persist in the absence of antigen expression or in the presence of intermittent low-level antigen expression.
The current antiretroviral therapy (ART) can effectively reduce plasma HIV loads to undetectable levels, but cannot eliminate latently infected resting memory CD4 T cells that persist for the lifetime of infected patients.
By tracking the fate of a group of immature cells that persist in the adult brain and spinal cord, Johns Hopkins researchers discovered in mice that these cells undergo dramatic changes in ALS, also known as Lou Gehrig's disease.
Muscle satellite cells are myogenic precursor cells that persist in mature skeletal muscle as quiescent cells [15].
This process of islet formation may also produce small isolated clusters of endocrine cells that persist throughout a lifetime.
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Of note, gBT-I.uGFP TRM cells co-localized with epidermal B16.gB.Tyr / .mCherry cells that persisted in the absence of macroscopic tumours, and such contacts lasted up to 2 hours (Fig. 3b, c and Supplementary Videos 2, 3).
The stem cells that persisted the longest were in the mushroom body, a region of the fly brain responsible for memory and learning that, in some ways, is like the hippocampus in humans.
Regression analysis showed significant induction of micronuclei in NHP blood cells that persisted with a gradual decline over the 8-month study period, suggesting long-term DNA damage in blood lymphocytes after WTLI.
Interestingly, the remaining Sox2+ cells that persisted in the CHI-treated cultures were predominantly T(Bra)+ (Fig. 3H).
The F4/AS01 vaccine elicited a high frequency of F4-specific polyfunctional CD4+ T cells that persisted until month 12.
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