Sentence examples for cells that mediate from inspiring English sources

This effect is essential for priming of CD8+ T cells that mediate systemic tumour rejection (abscopal effect) in the context of immune checkpoint blockade.

The infection induces Type 2 innate and adaptive (Th2) immune responses in parallel with a large expansion of regulatory cells that mediate immunosuppressive effects2,3,4, some of which have beneficial properties in allergy and auto-immunity5.

In one study the researchers found that in the presence of tumors, adipose-derived stem cells those in fatty tissue are more susceptible to becoming myofibroblasts, cells that mediate the typical stiffening of tumors, enabling their detection via palpation.

However, when implanted, the topology and ligand landscape of the material will determine the host molecules that bind and the type and behavior of cells that mediate the host response.

We hope our updated model centered around the AT2 cell as the initiator of disease provides a cellular framework that researchers can build upon and revise as they identify the specific molecular signals within and between alveolar cells that mediate the diverse pathologic features, so that targeted pharmacologic and cell-based treatments for patients can ultimately be engineered.

Transcriptional and posttranscriptional regulation of cytokine gene expression in HIV-1 antigen-specific CD8+ T cells that mediate virus inhibition.

Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine expressed by urothelial cells that mediates bladder inflammation.

Blocking L-type and R-type VGCC in DCs, primed T cells that mediated killing of M. tuberculosis inside macrophages.

We also demonstrate the existence of an alternate STAT6-independent pathway of IL-5 production by CD4+ and NK cells that mediates the development of eosinophils in bone marrow and their subsequent movement into the circulation.

In conclusion, we report for the first time the existence of a miRNA-regulated mechanism in human islet cells that mediates the suppressive effects of high glucose on insulin biosynthesis.

One such system utilizes an E2F1-luciferase transgene, expressed primarily in dividing cells, that mediates the release of light in the presence of the bioluminescent compound luciferin.