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Instead, there are many B cells that bind with low affinity to these determinants, a binding which is insufficient for their deletion or inactivation.
Combining the two approaches should enumerate cells binding tetramers via TCR pMHC interactions and exclude dumped cells that bind SA, MHC, or the dump-associated FP and those excluded by two-color analysis that bind the FP associated with the tetramers of interest in a non-specific manner.
Old mice also have more cells that bind individual or multiple distinct foreign-pMHCs, and the fold increase in pMHC-binding populations is directly related to their CD5 levels.
The researchers developed a test to find immune cells that bind to glycosaminoglycans.
FcRs are structures on the surface of certain cells that bind the Fc region of Abs.
They've identified more than 80 proteins in mouse cells that bind to Xist to help it do its job.
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IFN-β is an antiviral cytokine secreted from infected cells that binds to the IFN receptor on the surface of other cells.
The biological evaluation demonstrated that BNSBA selectively binds to apoptotic cancer cells and is localized within the cytoplasm of cells that bound annexin V on the plasma membrane.
The high magnification fluorescent images demonstrate that DFNSH is localized within the cytoplasm of cells that bound Alexa® 488 labeled annexin V on the plasma membrane.
CD154 is a cell surface molecule expressed on activated T cells that binds to CD40, an activating molecule on APCs.
In fibrotic livers, aHSCs were the principal cells that bound the carrier.
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