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Although some of the genomic sequence is lost when attempting MDA from single cells, substantial amounts of the genome (60 70%) can be obtained [24].
While no ERCs were detected in young wild-type cells, substantial ERC accumulation was observed in aged wild-type mothers.
In A549 epithelial cells substantial MCP-1 was constitutively expressed whereas little or no spontaneous IL-8 or RANTES was detected.
In cocultures of CD4+CD25+ T cells with CD4− T cells, substantial amounts of IL-10 were detected after J immunization depending on the cellular proportion (Fig. 3c) and independent of the effector T cell specificity (Fig. 3d).
> -wrap-foot> In MAL-overexpressing Schwann cells, substantial transcriptional reduction was detected for the glutamic acid decarboxylase 2 (Gad2/ Gad65), the asialoglycoprotein receptor 1 (Asgr1), the ectonucleoside triphosphate diphosphohydrolase 2 (Entpd2), and the intermediate filament keratin 23 (Krt23).
RelA was found mostly in the cytosol of both the T cells (substantial nuclear translocation does not occur by 10 min post-stimulation [ 8]) and the 3T3-APC fibroblasts (Figs. 3C, 4C).
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Although there is still no evidence that GSH is synthesized in nucleus of the plant cell, substantial amount of GSH can be recruited by plant nucleus at the expense of the cytosolic GSH pool [ 69].
Mbd3 knockdown cells showed substantial increased mRNA expression of trophectoderm lineage markers, a strong indication of trophectoderm differentiation.
Parasol cells exhibited substantial pairwise correlations, as has been observed in other species, indicating functional connectivity.
Application of Trac-looping to human CD4+ T cells revealed substantial reorganization of enhancer promoter interactions associated with changes in gene expression after T cell receptor stimulation.
Jenkinson, S.R. et al. Expression of the transcription factor cKrox in peripheral CD8 T cells reveals substantial postthymic plasticity in CD4 CD8 lineage differentiation.
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