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Current therapies often 'train' cancer cells shifting them to a novel attractor, which has increased metastatic potential and drug resistance.
Interestingly there is a small range for a B,2 for which there are two cycles of decreasing and increasing the growth rate, corresponding to type 2 cells shifting the production and then type 1 cells shifting the production (Supplementary Fig. 3).
Exposure to pathogens increased a variety of immune system components in their blood particularly subsets of specialized T cells—shifting the immune profile closer toward that of an adult human.
To develop an efficient algal culture system, sufficient mixing is obligatory in that it not only enhances mass transfer, but also improves frequency of algal cells' shifting between dark and light, which is crucial for improving photosynthesis efficiency (Abu-Ghosh et al. 2016).
In addition, differentiated spermatogonia can act as "potential stem cells", shifting their nature of transit-amplifying cells to self-renewal in order to rapidly recover spermatogenesis in depleted testes [59].
The shift is in all cases directed ventrally (n = 17/17, Fig. 5C), sometimes with a shift of more than one adjacent position, cells shifting from dorso-lateral to mid-ventral, for example (Fig. 5E).
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In addition, LOAD cells shift their energy production to glycolysis resulting in augmented ATP and lactate production.
To more finely trace how cells shift their expression program between infection co-stages we performed pseudotime analysis using Monocle27 (Methods).
From the reported data, efficient expansion of stem cells has been found to rely on glycolysis, while during differentiation stem cells shift their metabolic pathway to oxidative phosphorylation.
Moreover, the infiltration of microglia/macrophages significantly reduced and these cells shifted toward anti-inflammatory M2 subtype in the CNS after the vaccine treatment.
As this limit on responsive cells was tightened, the selectivity of the cells shifted from shallow to acute curvature.
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