The Polish police who arrested them gave them a small pen knife to cut their bread in the cell, reasoning that it would be too weak to use for escape.
Consequently, the code for an utterance is recorded in a cell where its reasoning component column meets its utterance type row (Fig. 2).
Some treatments for MM involve cell-based therapies in which patients are given autologous stem cell transplants, under the reasoning that this may recapitulate normal immune cells that may fight the disease [ 128].
By logical reasoning, tumor cells that depend mainly on OXPHOS for ATP generation should require elevated levels of heme and hemoproteins for proliferation and function.
Finally, we sought to determine if the epigenetic regulation of miR-200c expression in normal cells is conserved evolutionarily, reasoning that DNA methylation-linked control of miR-200c expression across mammalian species would provide further experimental support for epigenetic control of cell-type specific expression of miR-200c.
As an initial optimization, we performed cChIP-seq for H3K4me3 in K562 cells (Fig. 1b), reasoning that it is the most robust mark to ChIP and should perform best at a small scale.
To distinguish potential cortical actin nucleators, we examined the localization of the expressed nucleators in M2 cells using imaging assays, reasoning that proteins clearly localized to the cell periphery were good candidates for initiators of cortex growth, whereas nucleators strongly enriched in other locations were likely fulfilling other functions.
In conclusion, although care must be taken in applying this reasoning to cell types in which, for example, mitochondrial and cell turnover rates differ from those assumed here, or differentiation leads to tissue-specific selective factors acting on the mtDNA population, this formalism provides a general means of rigorously inferring embryonic heteroplasmy through genetic diagnosis sampling.
This in part follows the reasoning that cancer cells take advantage of the same robustness-enhancing mechanisms that normal cells exploit to maintain their physiological states.
Reasoning that stem cells might need a more natural, three-dimensional environment in which to grow and differentiate, Massachusetts Institute of Technology biomedical engineers Robert Langer, Shulamit Levenberg, and colleagues created an artificial scaffold to give the miracle cells enough physical support to aggregate and organize into larger structures.
Reasoning that germinal cells and planarian neoblasts may share a similar transcriptional signature, we compared our dataset with transcripts enriched in FACS-purified planarian neoblasts (Önal et al., 2012) to identify putative germinal cell-specific transcripts.
