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I could see lots of fat little larvae curled up in their cells, proof that the queen was alive and laying.
This seems to be the first time that a miniature organ has been coaxed to form from embryonic stem cells, proof that in the right circumstances the body is a self-assembling system.
The formation of normal sensory organs composed of both inner and outer cells (proof that N-on cells were formed) was used to assess the time required for Nts-1 receptors to recover their function at 18°C.
Histological examination of a reference biopsy (to exclude tumour cells, proof of follicle presence) is necessary.
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Schekman was confident what he had found would also apply to mammalian cells, but proof did not arrive until 1989, when his fellow Nobel prize-winner James Rothman revealed that protein machinery he had found separately in hamster cells which permitted vesicles' cargo to be transferred was encoded by genes that were equivalent in yeast.
Genetic inhibition of either HIF-1α or TGF-β in tumor cells provides proof of principle that these signaling pathways promote bone metastasis through tumor-autonomous effects.
Primer extension preamplification (PEP) and PCR were performed on the separated tumor cells as proof of ISET's applicability in cancer study.
To ensure that our results in the different cell types were not influenced by reduced cell survival during the temperature shift or transfection procedures we used trypan blue stainings on all cell types to proof cell viability.
Therefore, stringent controls for and prevention of mycoplasma contamination should be standard and should be sought before any cell experiment proof of a mycoplasma free-cell culture.
In other words, scientists had long thought that they knew how memories were formed and weakened, and now they had clear, cell-level proof of it, as well as a way of strengthening and weakening memories directly.
Taken together, the gene expression signature of hES SA02 cell line profiled by NeuroStem Chip is indeed characteristic for pluripotent stem cells, providing proof-of-concept.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com