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For example, the activity of the MEK ERK signalling pathway seems to reduce sensitivity to CDDP in ovarian carcinoma cells, whereas phosphorylation of MEK and ERK has been found to be essential for the CDDP-induced apoptosis in cervical carcinoma cells (Persons et al, 1999; Wang et al, 2000).
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Now, consider that each infected person yields 1 × 10 cells person-1 day-1.
However, earlier studies suggest that synchronized inhibition from Purkinje neurons could result in precisely timed spikes in the efferent cells (Person and Raman, 2012).
(See here for more.) DNA contains basic information that, when combined with the appropriate organic structures (in the egg) and context (the mother's uterus), will facilitate the growth of a single cell (the combined sperm and egg) into a multibillion-cell person.
That is, some genes vary in expression more from cell to cell, person to person, or treatment to treatment than other genes.
This is due to the highly variable nature of human immune cells from person to person.
Tebas, P. et al. Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV.
Bacalini, M. G. et al. Identification of a DNA methylation signature in blood cells from persons with Down Syndrome.
Rapid evaluation of therapies designed to preserve β cells in persons with type 1 diabetes (T1D) is hampered by limited availability of sensitive β-cell health biomarkers.
Tebas P, Stein D, Tang WW, Frank I, Wang SQ, Lee G, et al. Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV.
The sustained increase in red cells in persons who reside permanently at high altitudes is a direct result of the diminished oxygen pressure in the environment.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com