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Cells of origin in cancer.
Melanopsin in cells of origin of the retinohypothalamic tract.
Descending projections from the gigantocellular tegmental field in the cat: cells of origin and their brainstem and spinal cord trajectories.
By tracing cancers back to their cells of origin, Columbia researchers are learning why some cancers become aggressive.
SOX2 is expressed in benign and malignant chemical-induced skin tumours and in genetically induced skin tumours from different cells of origin.
Fusion-negative and fusion-positive RMS are distinct tumor subtypes, with different pathways of oncogenic deregulation, and likely divergent cells of origin (reviewed in ref. 1).
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Barker, N. et al. Crypt stem cells as the cells-of-origin of intestinal cancer.
(d) Basal cells could potentially function directly as the cells-of-origin for anaplastic variant PCa and/or indirectly as the cells-of-origin for adenocarcinomas via differentiation into luminal cells.
Defining the cells-of-origin for cancer is of great value for patient tumour stratification and delivering personalized treatment.
The open-versus-closed chromatin state within the cells-of-origin of cancer correlates with the uneven distribution of mutations.
To date, however, no direct evidence has identified the true cells-of-origin for all subtypes of lung cancer.
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CEO of Professional Science Editing for Scientists @ prosciediting.com