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But the truncated N-glycosylation pathways in insect cells limit its application on some glycoprotein expression (Jarvis 2003).
In addition in situ compression tests in a TEM have been carried out which show that cell boundaries, sub-cell boundaries and particles within the cells limit dislocation movement during deformation.
Issues related especially to nutrient and oxygen delivery to the cells limit tissue construct development to smaller than clinically relevant dimensions, which in-turn limits the ability for in vivo integration.
How do cells limit DNA pairing reactions to sister chromatids?
By recognizing and eliminating newly infected cells, virion-specific TH cells limit the spreading of infection and keep the pool of latently infected B cells small [22], [49].
Hadinoto et al [35] have demonstrated that high levels of EBV lytic replication during AIM results in very high levels of circulating latently-infected memory B cells; a marked reduction in peripheral blood EBV load is observed during convalescence as EBV-specific CD8+ T cells limit rounds of lytic viral replication and resultant seeding of the peripheral blood memory B cell pool.
Similar(38)
E-cadherin-mediated cell-cell adhesions limit cell motility and establish apical-basal polarity.
However, high cytotoxicity against normal cells limits the improvement of anticancer efficacy of anisomycin.
However, poor engraftment of transplanted cells limits the efficacy of the treatments.
However, the poor utilizability of blood cells limited the application of blood.
Antigen-independent tonic signaling by chimeric antigen receptors (CARs) can increase differentiation and exhaustion of T cells, limiting their potency.
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