Sentence examples for cells cycle arrest from inspiring English sources

They accumulated and localized in cell cytoplasm, and induced G0/G1 cells cycle arrest through regulation of AKT pathway and activation of downstream effector proteins.

Moreover, in a preliminary pharmacological study, 17b not only remarkably induced cellular apoptosis, but also clearly induced A549 cells cycle arrest at S phase.

Hereby, transfection of dsP21-397 causes BC cells' cycle arrest and impedes proliferation.

These data demonstrate that SI 34 is able to reduce the cyclin D1 expression in SH-SY5Y cells, suggesting a correlation between the reduction of this protein level, the cells cycle arrest and the inhibition of cellular proliferation.

Thus activation of cyclin kinase inhibitors P21Cip1 and P16INK4A can therefore inhibit pRb and other pocket proteins phosphorylation and prevent E2F transcriptional activity leading to very efficient cells cycle arrest in control cells.

As prolonged activation of DDR and cell cycle check-points result in permanent cells cycle arrest (cellular senescence; for a review, see [ 65, 66]), we next assessed the presence of senescent cells in cultures exposed to conditioned 'senescent' or control media using established markers of cellular senescence.

Rocaglamide treatment leads to cell cycle arrest.

(D) CBX6 induces cell cycle arrest.

Radiation-induced cell cycle arrest compromised by p21 deficiency.

Rocaglamide alone induced cell cycle arrest, but not apoptosis.

Fig. 2: Copanlisib causes a G1 cell cycle arrest.