Integral membrane proteins (IMPs) play a central role in cell communication with the environment.
We found that Ptbp2 controls a network of genes involved in cell adhesion, migration, and polarity, suggesting that splicing regulation by Ptbp2 is critical for germ cell communication with Sertoli cells (multifunctional somatic cells necessary for spermatogenesis).
The fibroblast growth factor (FGF) signaling system is a ubiquitous fast-acting cellular sensor of local environmental changes and mediator of cell-to-cell communication with broad roles in cellular homeostasis in development and adult organs.
The cell envelope represents the outermost layer of the bacterial cell that has as general functions the protection of the cell, communication with the environment, maintenance of cellular shape, stability, and rigidity of the cell, as well as allowing appropriate metabolism, growth, and division of the cell.
Endothelial cells are one origin of tumor vessels [23], and accumulating evidence has shown that cancer cell communication with endothelial cells via miRNAs in EVs is associated with angiogenic activity in tumors [24 27].
Previously cell-to-cell communication with extra-cellular growth factors has been shown to regulate the initiation of primordial follicle development.
The largest GO category represented in GV oocyte was related to cell communication with translation, transport, RNA metabolism, reproduction, and cytoskeletal organization and biogenesis also well represented (42.7% of the oocyte proteome).
MAPK pathway mediates cell communication with extracellular environments [ 34] and regulates a broad array of biological processes, including focal adhesion [ 37] that also controlling cell communication [ 35].
KEGG pathways that were enriched for bimodal genes include cell communication, ECM-receptor interaction, focal adhesion – all pathways that mediate cell communication with the extracellular environment (Table 3).
