Exact(3)
Dr. Keating, a vice president at the Novartis Institutes for Biomedical Research in Cambridge, Mass., believes stem cells can ordinarily undertake only very limited repairs of organs like the liver and heart, and that the scarring often seen in these tissues is a fallback mechanism put in place when the stem cells' capacities are exceeded.
To test this, a modified Transwell chamber assay was employed and the result showed that cells' capacities of migration and invasion were significantly increased upon infection (P < 0.05).
Our results suggest that the response to this combination treatment might depend on cells' capacities to repair DNA damage and assessing DNA repair capacities of tumor cells from patients undergoing clinical trials of PARPi could help to adjust radiation therapy schedules.
Similar(57)
In embryonic stem cells, for instance, they occur on genes that control the cells' capacity to specialize.
The established cardiovascular risk factors cause oxidative stress initiating a chronic inflammatory process which alters the endothelial cells capacity.
Altogether our results demonstrated that the constructed biosensor reported on the cells capacity to oxidize NADH, and more generally on the NAD(H) cofactor balance.
Anchorage-independent-growth is a measure of a cells capacity to grow in three dimensions, without contacting a basement membrane.
Morgan and colleagues also showed that desensitization limits alveolar type II cells' capacity to produce cAMP [ 40].
Interestingly, c-Fos overexpression in αvβ3-deficient osteoclasts substantially rescues the cells' capacity to organize their cytoskeleton [ 28].
High cell capacities and good cycling performance were demonstrated at room temperature.
These works demonstrate that those basal epithelial cells possess the stem cell capacities for self-renewal and multi-lineage differentiation.
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