Sentence examples for cells app from inspiring English sources

Samples consisted of confluent grown SH-SY5Y cells (APP or vector, untreated or treated for 24 h with GBE 100 µg/ml).

Indeed, real-time PCR assays revealed that in infected SH-SY5Y cells APP transcript levels progressively decreased starting from 4 h p.i. up to 18 h p.i. (Figure 2A).

However, in the embryo, pPPs never express Pax6 and never contribute to the lens, suggesting that, in these cells, aPP character must be actively repressed.

Although RhoH transduced donor cells allowed normal distribution of all lineages, the percentage of engraftment was severely reduced for RhoH overexpressing cells (app. 50%).

Over-expression of kinesin 1C, which is recruited in neural cells APP (amyloid precursor protein) transport vesicles, was not to date described in Mk cells.

Concerning 27-OH, it has been shown that this oxysterol, at the final concentration of 10 μ m, significantly reduced Aβ peptide production in primary human neurons (Kim et al., 2009), while in other papers, in 27-OH-treated SH-SY5Y cells, APP processing was found either similar to control values (Famer et al., 2007) or significantly enhanced (Prasanthi et al., 2009).

Consistent with its function, Pax6 is initially confined to future lens and olfactory cells (aPPs).

The amount of insulin mRNA available for translation is dependent on both the rate of insulin gene transcription and the stability of the transcript [7], [26], but due to the high copy number of insulin mRNA in the β-cells (app. 50 000 copies/cell at basal conditions), the level of insulin mRNA is controlled mainly by changes in mRNA stability [6], [21].

We also observed that the secretion of sAPPβ into the medium was diminished in CHO cells expressing APP A673T (APP A673T cells) (Fig.  1); however, the levels of C99 carrying A2T (C99 A2T) in APP A673T cells were not affected, which was in agreement with the study reported by Benilova and colleagues (Fig.  1b and c) [ 19].

We found that the level of C99 in cells expressing APP A673T was indistinctive of that observed in cells expressing wild-type APP, although the release of sAPPβ was significantly reduced in the APP A673T cells.

As seen in APP-depleted neuroblastoma cells before, APP-KO neurons failed to show sAPP α-dependent Akt activation that could, however, be readily detected in wt neurons.