Sentence examples for cell survival changes from inspiring English sources

Statistical significance of cell survival changes with the application of nanoparticles is calculated using a Kruskal Wallis test.

Although levels of intracellular iron, ferritin/CD71 protein and reactive oxygen species did not correlate with iron-induced cell survival changes, we identified mitochondrial damage (via TEM) and reduced expression of outer mitochondrial membrane proteins (translocase of outer membrane: TOM20 and TOM70) in cell lines sensitive to iron.

This was confirmed by cell survival assays, showing a 10-fold increase in MPA cytotoxicity (50% reduction in cell survival changed from 12.2 ± 0.3 μM to 1.33 ± 0.01 μM by MPA + CsA; P < 0.001) and in perfused kidneys, showing a 50% reduction in MPAG excretion (P < 0.05).

However, although the changes in TOM20/70 proteins were clearly noted with 100 μM FAC (in addition to reduced cell survival response), changes in these OMM proteins occurred to a lesser extent with HTF (10 50 mg/ml which is 250 μM) with no change in cellular viability (results not shown).

TGF-β has a number of tumor cell-targeted effects that could contribute to the enhanced malignancy, including enhancement of tumor cell migration and invasion, direct effects on tumor cell survival, and changes in the composition of secreted growth factors and extracellular matrix components [14], [35].

Treatment resulted in compromised cell survival and changes in cellular morphology reminiscent of degeneration.

Bmi1 overexpression in postmitotic cerebellar granule cells resulted in increased cell survival and changes in the mitochondrial cell death pathway and survival genes but not antioxidant genes.

Recently, two interesting proteins with a marked regulatory effect on cell survival through changes in Ca2+ have been identified in the zones of mitochondria-ER association.

Addiction of cancer cell survival to metabolic changes opened new therapeutic windows suggesting the possibility of targeting specific metabolic alterations (Vander Heiden, 2011).

Therefore, the essentiality of CBF1 in cell survival has been changed during the evolution of aerobic fermentation, but it was not clear about the cause of lethality.

Furthermore, SDF-1 and VEGF interact synergistically to promote vascular endothelial cell functions, such as cell survival, cell migration and changes in gene expression [ 37, 38].