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Cell surface reception of Sonic hedgehog (Shh) must ensure that the graded morphogenic signal is interpreted accordingly in neighboring cells to specify tissue patterns during development.
This ability requires a cell surface reception system that can transform the graded Shh signal into different levels of signaling output, but how this is accomplished is poorly understood.
Cell surface reception of Shh signaling is a multistep process that entails, but is not limited to, ligand engagement, reciprocal movements of Ptch1 exiting from and Smo translocating into the primary cilium, and activation of the G-protein-coupled Smo by still-controversial mechanisms (Ogden et al., 2008).
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HGF's source, reception by, and effects on prostate cancer cells are discussed in many review articles, as is the Met protein, the only known cell surface receptor for HGF [ 16- 21].
In conclusion, this study reveals for the first time that endometriosis can affect the regulation of PGE2 and PGF2 α activity at the points of reception on the cell surface and transport into the target cells.
T-cells can be differentiated from other lymphocytes like B-cells because they contain proteins called T-cell receptors (TCRs) on their cell surface.
cell surface or 2).
Cell surface staining was performed.
cell surface.
mRNPs containing mRNAs encoding functionally related proteins could be predocked to a specific signal-receiving component, such as cell-surface receptors or adaptor proteins, to allow the swift translation of subcellularly targeted mRNAs in the vicinity of signal reception by bypassing the rate-limiting initiation step.
The CD44 is a cell-surface glycoprotein.
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