Sentence examples for cell specificity and from inspiring English sources

Furthermore, the dynamic relationships between protein function, its cellular location (including its intracellular location, cell specificity and developmental specific expression) and how this relationship influences the biological processes a protein is involved in are not currently represented by GO.

However, due to the fact that all the arginine-rich cell-penetrating peptides (CPPs) induce a strong non-specific cell binding, they lack cell specificity and this remains the major impediment to development.

Current methods to model injury suffer from a lack of cell specificity and reproducibility.

CPPs with high internalization, cell specificity, and low cytotoxicity have been considered to increase the applicability for cell engineering.

Furthermore, they showed cell specificity and significantly higher photostability than that of a pure organic dye label such as BODIPY.

Beyond demonstrating new principles of T cell receptor cross-reactivity, our results have implications for efforts to predict and control T cell specificity and cross-reactivity and highlight challenges associated with predicting T cell reactivities.

Although this field was actively explored in the pre-genomics era, the discovery of tumor suppressor genes and oncogenes dampened interest in metabolism as a potential source of cancer cell specificities and related therapeutic targets.

Oncolytic measles viruses (MV) derived from the live attenuated vaccine strain have been engineered for increased tumor-cell specificity, and are currently under investigation in clinical trials including a phase I study for glioblastoma multiforme (GBM).

To better understand the contribution of epitope targeting and conservation to immune control, we compared the CD8+ T-cell specificity and function of B*27/57neg LTNP/EC (n = 23), B*27/57pos LTNP/EC (n = 23) and B*27/57neg progressors (n = 13).

Addition of β-lap to short-term FK866 treatment resulted in enhanced tumor-cell specificity and efficacy, not typically found with FK866 treatment alone.

One of the most promising costimulatory targets is OX40 and its ligand, OX40L, which has relative T-cell specificity and is not expressed on naive T cells.