Mechanisms of aminoglycoside ototoxicity and targets of hair cell protection.
These mechanisms are reviewed in regard to established and potential future targets of hair cell protection.
Ishida, Y. et al. Autophagic elimination of misfolded procollagen aggregates in the endoplasmic reticulum as a means of cell protection.
Smyth, M.J. et al. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) contributes to interferon gamma-dependent natural killer cell protection from tumor metastasis.
This capacity was not affected by the introduced changes abolishing its cell surface binding ability, since E194GAGmut also blocked the IFN-mediated cell protection (Fig. 2b, left panel).
Second, ALDH1 was shown to contribute to cell protection from aldehyde-induced toxicity by removing reactive aldehydes such as 4-hydroxy-2-nonenal47 4-hydroxy-2-nonenal47 4-hydroxy-2-nonenal47 4-hydroxy-2-nonenal47
Anthocyanins (blueberries, strawberries, raspberries, blackberries, grapes, cherries, red peppers, eggplant, red cabbage) offer antioxidant cell protection and may help prevent binding of carcinogens to DNA.
We recently demonstrated that honokiol inhibited arterial thrombosis through stimulation of prostacyclin (PGI2) generation and endothelial cell protection.
The current study is designed to investigate its mechanism of stimulation of PGI2 generation and cell protection.
Their potential applications are also discussed, including cell protection, cell labeling, targeted delivery and in situ regulation.
In summary, all leaf extracts form WBM variety and cultivars showed antioxidant, cell protection, and anti-melanogenic activities.
