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The induced pluripotent stem cells (iPSCs) technology enables the creation of cell models of progeria and geriatrics in laboratory conditions, for studying disease mechanisms and drug screening.
Open image in new window Figure 4 Phenotypic analyses of HGPS-MSCs and WS-MSCs indicate different kinetics between cell models of two different progeroid syndromes.
For the computational analysis of the damage mechanisms, 3D multifiber unit cell models of GFRP composites and X-FEM approach to the fracture modeling were used.
A new software and approach were developed for the automatic generation of finite element unit cell models of nanocomposites with inclusions of arbitrary and complex shapes.
Furthermore, P3A1-MWCNTs are cytotoxic to several cell models of breast cancer and induce S-phase cell cycle arrest and non-apoptotic cell death in breast cancer cells.
Here, we review how human pluripotent stem cell models of pancreas development have emerged and became an important tool to study human development and disease.
First, the unit cell models of 3D 4-directional braided composites with different braiding angles and fiber volume fraction were built up using ABAQUS.
The comparison of the experimental and calculated bed expansion data showed that the capillary and cell models of the beds are not correct for describing the flow of shear thinning polymer solutions through fluidized beds.
The phenotypes observed in the different cell models of PINK1 loss-of-function are summarised in Table 1.
We found significantly elevated levels of H2O2 in three cultured epithelial cell models of CF, one primary and two immortalized.
While similar observations have been observed in cell models of other polyglutamine diseases [24] [26], no impairment was observed in a polyglutamine-expanded ataxin-1 cell model using UFD or N-end rule UPS reporters [27].
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