Sentence examples for cell lifespan from inspiring English sources

Activating telomerase, an enzyme which lengthens the telomeres, may extend cell lifespan.

Let us consider the consequences of CD8+ T cell cytolysis, when the course of the acute phase of infection in different animals varies only because of different infected cell lifespan.

Disruption of telomerase activity in human normal cells slows cell proliferation, restricts cell lifespan, and changes the maintenance of the 3' single-stranded telomeric overhang without changing the rate of overall telomere shortening [25], [26], [62].

Most somatic cells are reported to express low levels of hTERT protein [27] [30] and disruption of the activity in normal cells slows cell proliferation, restricts cell lifespan, and alters the maintenance of the 3'-single stranded telomeric overhang without changing the rate of overall telomere shortening [25], [26].

To describe such causes, we have identified, for each child, both the mechanistic pathway leading to their anaemia (failure of red cell production, reduced red cell lifespan, or loss of red cells through haemorrhage) and the etiological factors that operated through these mechanisms (reported earlier [10]).

22 The implementation method of the cell lifespan model is detailed in Supplementary Figure S2.

Additionally, an in vitro study demonstrated that a culture of human satellite cells with ROS-inducing hydrogen peroxide (H2O2) reduced cell lifespans and proliferative capacities [ 135].

Past experimental studies [ 14, 19, 21] and the analysis of our experimental data (see below) suggested that the distribution of the cell lifespans could differ substantially depending upon the type of transformation undergone by the cells.

Stivers, Kimmel, and Axelrod [ 31] investigated branching process models of the inheritance of cell lifespans, whereas Boucher et al [ 32] and Hyrien et al [ 19] proposed branching process models for the inheritance of cell fate.

The technique improved cells' lifespan and function.

Possible mechanisms are genetic traits (18), aging (19), differences in erythrocyte environments (20), heterogeneity in red-cell lifespan (21), and racial differences (22).