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Whilst the performances of MEMS devices are comparable to traditional approaches, the suitability for cell level studies might be compromised.
This demonstrates the sensitivity of our assay for single cell level studies of cell signaling pathways.
At a single cell level, studies reveal substantial tumor heterogeneity [ 8].
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In case of cell level study and output buffers, the answers to the six main questions lead to a tree including 14 realistic switch and traffic types.
Our single cell level study results are consistent with a positive feedback loop at the population level [13].
As single-cell level studies cannot capture the emergent properties of an organized tissue, researchers should test their hypotheses in higher-order systems to gain a more thorough understanding of functions within the human body and to design therapeutics in an informed manner.
Microfabricated devices have great potential in cell-level studies, but are not easily accessible for the broad biology community.
However, single cell level genomic studies require amplification by a factor of a billion to reach detection levels from a few femtograms of mRNA present in a single cell.
With the continuous development, in the last decades, of analytical techniques providing complex information at single cell level, the study of cell heterogeneity has been the focus of several research projects within analytical biotechnology.
Recent software solutions from cell to canopy level studies have been organized in an online database [ 31] (www.plant-image-analysis.org).org
The mean blast cell level in our study, however, was found to be 85% (range: 52 100) meaning this issue may be avoided.
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