Cell length distributions obtained from microscopic observation.
The depletion of EB1 did not interfere with cell elongation: The cell-length distribution (data not shown) and the mean cell length in EB1-depleted cells (108.9 ± 19.9 μm) were very similar to those of control cells.
However, recent studies based on real time lineage analysis of cell division patterns in the L1 have revealed a wide range of cell cycle length distributions in the inflorescence meristem of an individual plant, which might explain the variability of our data [16].
Our result is also similar to the motion of motile flagellated prokaryotic bacterial cells that have Poisson distributed runtimes [33]; given the essentially constant speed with which the bacterial cells move, the run length distribution of bacteria can also be expected to be exponentially distributed.
In order to assess the multi-modality of the major peaks in the cell-free DNA fragment length distribution, we fitted a 3-component Gaussian mixture model to the inferred lengths in both a genome-wide and per chromosome basis.
We examine the periodicity in cell-free DNA fragment length distribution using Fourier analysis and confirm the ~180 and ~10 bp periodicity due to the two levels of cleavage which others have only assessed visually.
To determine whether hTERT was strictly regulated in the binary system, we examined telomerase activity and telomere length distribution in cell populations containing hTERT in a presumed 'OFF' or 'ON' orientation.
To assess the unspecific effects of siRNA transfection we compared the period length distribution between cells transfected with a scrambled siRNA and untransfected cells.
The comprehensive understanding of the impact of short telomeres on the onset of senescence in S. cerevisiae has been hampered by the lack of knowledge of the actual telomere length distribution within cells.
The similarity of the distributions for cell length, surface area and volume at mitosis were compared in the wild-type, rga2Δ and rga4Δ mutants using the Jensen Shannon distance.
Thus, to assess the relative contribution of short telomeres to senescence and their interference with other pathways, knowledge on the telomere length distribution within a cell emerges as an indispensable step.
