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The other was for the group that controls the process by which a cell kills itself, which is known as apoptosis.Apoptosis is an essential act, not a casual one.
L-PAM as a single agent was highly active against MM.1S, KMS-12-PE, MOLP-2 and NCI-H929, inducing ⩾2 logs of cell kills at the maximum dose (50 μ M).
Since the system is dominated by the direct cell kills shortly after chemotherapy application, the interaction between tumour and immune system can be neglected for estimating p T and p E. The right-hand side of model equations is Lipschitz continuous only for T bounded away from zero.
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NK cells eradicate tumors through multiple killing pathways, including direct tumor cell killing.
In virotherapy, tumor cell killing is achieved by oncolysis – virus replication induced cell killing [ 3].
Pretreatment with orlistat reduced the cell killing activity of PPD.
Indeed, addition of free targeting peptide reduced cell killing.
In consequence, once tumor cells are arrested and synchronized they can be targeted with a cytotoxic agent, thus maximizing cell kill fraction and minimizing normal cell killing.
Combination treatment resulted in broadly effective cell kill of p53 WT and p53-negative cancer cells.
Targeted cell killing with DT5F11 was seen only in GD2 positive cells.
Our data revealed that OPF SMA microgels prolonged the cell killing effect of DOX.
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