Qi, H., Cannons, J.L., Klauschen, F., Schwartzberg, P.L. & Germain, R.N. SAP-controlled T-B cell interactions underlie germinal centre formation.
Qi, H., Cannons, J.L., Klauschen, F., Schwartzberg, P.L. & Germain, R.N. SAP-controlled T B cell interactions underlie germinal centre formation.
Alterations in pericyte-endothelial cell interactions underlie microvascular complications [ 40].
Tantalizingly, while some of the cellular responses and some of the cell-cell interactions underlying adjuvant effects are understood in principle, this understanding falls crucially short of allowing the design of vaccines to produce lasting immunity of the appropriate kind to all the infectious diseases flesh is heir to.
Kubu, C.J. et al. Developmental changes in Notch1 and numb expression mediated by local cell-cell interactions underlie progressively increasing delta sensitivity in neural crest stem cells.
Such studies will provide a detailed model for understanding the cell behaviors and interactions underlying tail extension, a process that is common to all chordate lineages.
Altered cell-matrix interactions underlie the pathogenesis of OA [ 36], especially for late disease stages investigated here [ 34].
HGF/Met signaling is critical for epithelial-mesenchymal interactions underlying normal functions including cell migration, morphology, cell division during tissue remodeling and repair, and organogenesis during embryonic development [3],[4].
Understanding the protein interactions underlying Fas-mediated cell death pathways is potentially important for identifying novel targets and agents for the effective initiation of cancer cell death.
We envision future uses for the technology that can help decipher the tangled web of interactions underlying for example cancer drug resistance and stem cell differentiation, or design advanced synthetic gene circuitries," said Church.
