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Employing this in vitro live cell imaging setup, we have compared T cell interactions on pMBMECs with those on bEnd5 cultures [ 15].
Recently, a first report appeared on the influence of neurones in the central nervous system on T cells and the potential role of neurone-T cell interactions on experimental autoimmune encephalomyelitis [ 17].
To study the effects of stromal epithelial cell interactions on prostate cancer metastasis, we have used primary human prostatic stromal cells derived from malignant and non-malignant tissues and established epithelial cell lines from normal (PNT1a and PNT2-C2) and tumour (PC-3, DU145 and LNCaP) origins.
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Celi, A., Lorenzet, R., Furie, B. & Furie, B.C. Platelet-leukocyte-endothelial cell interaction on the blood vessel wall.
In contrast, CIA-resistant FVB animals did not respond with enhanced leucocyte endothelial cell interaction on CFA/collagen II exposure, with findings equivalent to those in CFA treated control animals (Figs 3 and 4).
The aim of this work was to determine the effect of platelet-cancer cell interaction on TF and "Metastasis Initiating Cell (MIC)" marker levels and migration in ovarian cancer cell lines and cancer cells isolated from the ascetic fluid of ovarian cancer patients.
While the CAI metric captures impact of cell-to-cell interactions on the microenvironment (computed over cell-graph edges), here we introduce a new metric computed for an individual cell to complement it.
We speculate that abnormally large amounts of GLTP or FAPP2 in the cytosol could limit availability of the simple glucosylceramide (GlcCer) produced by the cytosol-facing GlcCer synthase and needed for generation of higher GSLs involved in cell-cell interactions on the cell surface.
In mouse embryonic stem cells the impact of cell-cell interactions on transitions between Nanog-high and Nanog-low cells [ 48, 49], or on the cell fate decision between epiblast and primitive endoderm [ 50] could be analyzed with our proposed method.
This method is particularly suitable for studies of cell-cell interaction on cell migration [ 18].
While the cell density decreased on as-deposited 1D Al2O3 nanostructures, we observed enhanced cell proliferation and cell-cell interaction on recombinant phage overcoated 1D Al2O3 nanostructures.
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