Sentence examples for cell impairment from inspiring English sources

"Induction of cell impairment" can include damage of cell membranes and cytoskeleton, impaired energy charge or disturbances of the cell homoeostasis.

Wang and Fan [62] conducted studies showing that the level of the rats' pulmonary cell impairment, inflicted by the intratracheally instilled TiO2, clearly depended upon the diameter of its particles.

Beside the potential effect of horizontal cell impairment on scotopic vision additional effect can be hypothesized.

Reduced lymphocyte production as a consequence of follicular and T cell impairment could explain why significantly lower numbers of white blood cells, and specifically lymphocytes, have been reported in old common shrews [46].

Several models of vitamin B12 deprivation have been developed in vitro and in vivo to determine the biochemical and molecular mechanisms of the cell impairment caused by vitamin B12 deficiency.

While it remains controversial if all observed types of oligomers are indeed on-pathway intermediates [4], [15], [21], an increasing amount of experimental evidence points to soluble protein oligomers as the primary cause of cell impairment and dysfunction in the pathogenesis of neurodegenerative diseases and various amyloidoses [3], [15], [21] [25], [27].

While T-cell defects are reversed in a minority of infected individuals who succeed in controlling the infection, the T-cell impairment becomes progressively more profound as infection progresses to chronicity.

The lack of such an activity in humans, owing to a genetic disorder, causes T-cell impairment, and drugs that inhibit this enzyme may have the potential of being utilized as modulators of the immunological system to treat leukemia, autoimmune diseases, and rejection in organ transplantation.

For these studies, H2O2 was used to induce the reactive oxygen species (ROS) generation, which lead to cells impairment or death.

In the corresponding tissues and cells, impairment in bone morphogenic protein (BMP) and TGF-β signaling were observed.

In pancreatic β-cells, impairment in the assembly of the exocyst results in a decrease in the number of secretory granules docked at the plasma membrane and in defective insulin release [14].