Sentence examples for cell helper from inspiring English sources

It may be beneficial to provide a CD4 T cell helper peptide with a vaccine particularly in the case of a poorly immunogenic antigen.

We propose that a combination of suboptimal type I IFN production, poor CD4+ T cell helper function and inefficient DC licensing likely contribute to this transient response.

Such a T cell helper peptide must be promiscuous in its ability to bind a broad range of MHC class II alleles due to broad allelic variation in the human population.

In addition, the group pTPA.GPI-PA63 also displayed low magnitude MHC-II restricted (CD1d-independent) NKT cell and CD4+ T cell helper responses in response to non-GPI attached PA63 peptides which overall resulted in the heightened responses seen for this group.

These proteins go on to become either new virions within the cell, helper proteins, which help assembly of new virions, or proteins involved in cell lysis.

Four major CD4+ cell helper subsets are currently recognized, Th1, Th2, Th17, and follicular Th (TFH) [22], [24], [25].

It is possible that chemo-vaccination-induced anti-SHIV CD4+ T cells did not differentiate enough to become efficient B cell helpers.

Specifically, macrophages, dendritic cells, neutrophils, natural killer cells, B cells, T helper cells, complement proteins, and pathogenic bacteria are present in the model.

Furthermore, the OspA leader peptide has been fused to different proteins to generate potent lipo-antigens that induce strong B (IgG) and T-cell (helper CD4+ and cytotoxic CD8+) responses [44], [45].

The immunophenotypes of K5-Stat3C and K5-TGFβ1 models were comparable in most respects, although for K5-TGFβ1 lesions, there was stronger indication of T-cell infiltration, with significant CD4+ T-cell, CD8+ T-cell, helper T-cell and regulatory T-cell signatures (P<0.05; Figure 9).

Another reason for the lower NAb response could be inefficient T-cell helper response.