Sentence examples for cell hallmarks from inspiring English sources

The sequential changes that transform glial (precursor) cells into tumor cells fit well with the cancer cell hallmarks encountered in many other tumor systems [ 52].

The therapeutic goal is to reduce the broad toxicity associated with many of the microtubule chemotherapeutics and direct the treatment at malignant cell hallmarks.

Hepatic stem-like cells derived from SSCs could differentiate into small hepatocytes based upon their morphological features and expression of numerous hepatic cell markers but lacking of bile epithelial cell hallmarks.

TNFα has been implicated in airway inflammation and hyperresponsiveness and the regulation of immune cells, hallmark features of asthma [ 20].

In eukaryotic cells, the hallmarks of apoptosis-like cell death include the fragmentation of nuclear DNA and histone H2B pH2BS14.

Inactivation of tumour suppressors and activation of proto-oncogenes leads to uncontrolled growth and cell division, hallmarks of tumour development.

More intriguingly, however, this could be due to neuronal mechanisms being appropriate for membrane 'excitability' and hyperactive cell behaviour, hallmarks of metastasis.

Our results suggest that cells at early stages of execution of the apoptotic program, even after Cyt c loss, can be recovered to cells with hallmarks of normal (healthy) cells.

We have previously demonstrated that the presence of the ITD mutation in AML was correlated with an aberrant accumulation of cells with hallmarks of arrested dendritic cells [ 14].

Pustule formation and dermal infiltration of mast cells, eosinophils and CD4+ T cells are hallmarks of the acute phase of atopic dermatitis in humans.

Like early observations in animals, models of papillomavirus-mediated transformation in human cells demonstrated hallmarks of EMT including induction of spindle morphology [13].