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Although ALF and other germ cell genes are normally expressed only in germ cells, they typically will show some activity when introduced into somatic cells.
A global analysis is shown in Figure 1b, and the results for a subset of stem cell genes are displayed in Figure 1c.
Somatic mutations in cancer cell genes are classified according to their functional significance.
Gene set enrichment analysis showed that stem cell and immature T cell genes are enriched in the established tumors.
For example, the node supporting Metapterygota (Odonata + Neoptera) is stabilized when all cell genes are concatenated (85) and also when 35 info genes are concatenated.
Mutations in cancer cell genes are broadly categorized as those that provide malignant cells with a proliferative or survival advantage, collectively termed "driver" mutations, or those that do not, which are therefore termed "passenger" mutations.
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Remarkably, the suppression of B cell genes was persistent when patients' samples were analyzed 1 month after the acute infection.
We asked whether EBV promoters and cellular genes characteristic of embryonic stem cell genes were transcribed in mESCs cells stably carrying the recombinant EBV genomes.
Expression of many endothelial cell genes were downregulated in culture especially Tie-1 and eNOS.
The normal-breast-like samples resembled normal breast tissue samples: basal epithelial cell and adipose cell genes were relatively highly expressed and luminal epithelial cell genes were expressed at relatively low levels.
Using more contemporary technology, it has been shown that T-cell genes are up-regulated during relapse of MCD, findings that may provide objective support for the old Shalhoub hypothesis [ 14].
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