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A protein's subcellular location can lead its specific function and critically influences cell functionality.
We generated an Aldh1b1-knockout mouse line (Aldh1b1tm1lacZ) and used this to study pancreatic development, beta cell functionality and glucose homeostasis in the absence of Aldh1b1 function.
Increased age is further associated with diminished T cell functionality, reduced memory T cell populations, and fewer numbers of properly functioning CD8+ cytotoxic T cells (Effros 2004).
The increased bcl-2 expression evident in zVADfmk/zLLYfmk sets is functionally relevant as bcl-2 has been reported to augment the stem cell functionality [34].
Both assays revealed significant and comparable loss of cell functionality that was confirmed by DNA assay.
Moreover, monitoring of cell functionality was demonstrated on a mouse model of Duchenne muscular dystrophy.
Maintaining microbial cell functionality and integrity is required to pass on random mutations to the next generation.
When the degradable material is in contact with host tissue, there exists robust and dynamic microenvironment controlling the cell functionality.
Analysis of the genome and proteome assumes the focus of attention in efforts to relate biochemical coding with cell functionality.
The results further support the idea that cell depolarisation indicates a decline in cell functionality due to energy depletion, but does not involve cell death.
The aim of the current study is to determine the feasibility of introducing fuel cell functionality on the surfaces of carbon-based composite materials.
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