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This is a universally accepted cell elimination process in unicellular and multicellular organisms.
The efficiency of infected cell elimination correlated with HIV Gag expression.
Blocking the PD-1/PD-L1 pathway can revert this condition, promoting cancer cell elimination by activated T-cells.
Here we demonstrate this antibody's highly efficient cancer cell elimination in a dose-dependent manner in a CD20-expressing B lymphoblastoid cell line in vitro.
Therefore, the control strategies (for instance, at least a certain amount of external effector (s_{1})) that will reduce (R_{s}) to within 1 are of great importance for the possible tumor cell elimination.
When clonogenic cell recovery rates were determined, HuM195/rGel alone did not affect normal peripheral blood progenitor cells, whereas HuM195/rGel plus freeze/thaw provided 2 logs of tumor cell elimination in our purging model.
To design a mouse model for vestibular hair cell regeneration research, an aminoglycoside-induced method of complete hair cell elimination was developed in our lab and applied to the murine utricle.
The major mode of red blood cell elimination appears to be extravascular destruction due to a massive erythrophagocytosis in spleen and liver [6].
Apoptosis, or programmed cell death, is a highly ordered mechanism of cell elimination which is involved in many processes such as embryogenesis, metamorphosis and tissue homeostasis [4], 5.
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In HIV infection, NK-DC interaction was found defective in HIV-1-infected viremic, but not aviremic patients, characterized by abnormalities in the process of reciprocal NK-DC activation and maturation, as well as a defect in NK-cell elimination of iDCs [30].
Alteration of NK∶DC cross may also lead to a defect in NK-cell elimination of iDCs, as reported in chronically HIV-infected patients [30] and associated with the resistance of HIV-infected DCs to apoptosis induced by NK cells (Melki MT, Saïdi H, Gougeon ML, submitted to publication).
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