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Our results showed that lead induced (1) a decrease in cell viability (MTT), (2) cell distortion and cohesion loss, (3) superoxide anion production and lipid peroxidation.
Under this condition, cells were able to move and grow within the 200×200 µm space without cell distortion, and the distance to the objective lens was kept constant to avoid changing focus.
Subtle cell distortion was detected after only two doses (necropsy at 28 42 days post-injection).
Cell distortion and membrane deformation consequent to asbestos treatment correlate with a clear increase in the ratio of intracellular Na+:K+ ions.
Although it is not clear if PHD2 associates with mitochondria, cell distortion in tumor vessels has been described in PHD2 haplodeficient mice.
However, in particles of smaller size (∼250 μm), there was evidence of significant levels of cell distortion and rupture in all areas of the almond particle, not just at the fractured surface.
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We show that, for sufficiently small grid displacement, this method also minimizes the mean grid-cell distortion, measured by the trace of the metric tensor.
Visualization of bacterial cells under scanning electron microscopy (SEM) showed enlargement of the cells, distortion of cellular membrane and possible leakage of cytoplasm after 10 min of exposure to photoactivated TiO2.
In senescent cells, distortion of the ellipsoid-like nuclear shape and lamin A folds protruding into the nucleoplasm have been described [ 29], which may also contribute to redistribution of telomeres in senescent cells.
Chondrocyte mechanotransduction is poorly understood, but may involve cell deformation and associated distortion of intracellular organelles.
Combining the three elements of the prior probability (distributions of molecular concentrations), the cell data (distortion tolerance of the cellular system), and the distortion function then allows cell fate decisions to be based on minimizing the mutual information between input and output.
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CEO of Professional Science Editing for Scientists @ prosciediting.com