Sentence examples for cell disaggregation from inspiring English sources

In the present study, a search for TTSuV genomes was carried out in cell culture lineages, in sera used as supplement for cell culture media as well as in trypsin used for cell disaggregation.

Loss of E-cadherin promotes metastasis by inducing cancer cell disaggregation, activating specific downstream signal transduction pathways, and causing epithelial-mesenchymal transition (EMT), which facilitates metastasis.

Briefly, islets obtained from five pancreases were washed 12 times in KRB and exposed for 10 min to free Ca2+- and Mg2+-KRB to allow cell disaggregation.

The factors investigated included: culture ICD and duration, temperature, media pH, aspiration and dispensing flow rates, applied shear rate, trypsinization time, cell disaggregation conditions, relative centrifugal force, centrifugation time, and cell pellet resuspension rate.

When UKF-NB-4 cells were exposed to VCR (UKF-NB-4VCR), NCAM partially disappeared from the cell surface and the tumor aggregates became smaller by cell disaggregation (figure 4).

Unlike the culturing and passaging of most lines where the majority of cells survive disaggregation and go on to proliferate until the culture becomes confluent, during passaging in the NSA, the majority (>90%) of the cells die or do not further proliferate.

Since our experiments have been performed with fresh breast tumor samples which provide only limited quantity of cells after disaggregation we were not able to apply alternative test systems such as MTT or XTT assay to validate the outcome.

Modulation of cell structure by disaggregation and reassembly of cytoskeletal subunits is common to all cells, as is ubiquitination of many of the signaling proteins that control this process.

However, whereas these germ cell aggregates underwent "disaggregation" in controls between E17.5 and E21.5, this process failed to occur by E21.5 in DBP-exposed animals.

Ultrastructural changes were determined at 72 h by scanning electron micrographs which confirmed the damage of epidermal and root cap cells and the disaggregation and destruction of root tip cells.

We have compared the response to a number of cytotoxic drugs of cells treated either within intact multicellular spheroids or as isolated cells following spheroid disaggregation.