Sentence examples for cell determinants from inspiring English sources

While it may not be feasible in clinical studies to assess whether AQP4-specific T cells participate directly in NMO pathogenesis, now that we have discovered the T cell determinants of AQP4, it should permit investigators to determine the relative contribution of these subsets of AQP4-specific T cells in the initiation of CNS inflammatory responses in models.

How does immunotherapy affect the landscape and function of T cells, and what are T cell determinants of responsiveness to immunotherapy?

To test our hypothesis, we first defined unique T-helper cell determinants on 1007 (clade B) and UG92005 (UG, clade D) gp140 envelope proteins delivered by DNA vaccination.

Two synthetic genes were designed and engineered to encode for multimeric luteinizing-hormone-releasing hormone (LHRH) peptides linked to T cell determinants.

We used a high throughput ELISPOT approach to test for responses to every possible 9-mer determinant within the 191 residue hepatitis C core protein in addition to 61 previously defined CD8 cell determinants.

Thus, we have identified T cell determinants in mice from WHV core and surface antigens that have important value for designing and evaluating an effective vaccine against hepadnavirus infection.

In addition, the expression of the stem cell determinant, WUS, increased in the ag-1-/+ crc-1 mutant relative to the crc-1 mutant (Supplementary Fig. 3).

To investigate the effect of YUC4 misexpression on the floral meristem indeterminacy phenotype at molecular level, we examined the expression of a stem cell determinant gene, WUS7 (Fig. 5n t).

The phospholipid phosphatidylinositol-4,5-bisphosphate (PtdIns(4,5 P2) is now well established as a host cell determinant of Gag binding to the plasma membrane (see the main text), and a number of host proteins have also been implicated in various aspects of Gag localization, membrane binding and assembly16.

The Th-B epitope hybrid peptides contained the HIV gp120 Th cell determinant, T1 (amino acids [aa] 428-440 -synthesized 428-440 -synthesized0 V3 loop peptides, which contain B cell epitopes that induce anti-HIV-neutralizing antibodies (SP10IIIB [aa 303-321] and SP10IIIB [A] [aa 303-327]).

These results indicate that p24-35 is the core immunodominant AQP4 T cell determinant in C57BL/6 mice.