Sentence examples for cell destabilization from inspiring English sources

We hope the visual and quantitative data will be helpful in analyzing the differentiation process of ADSCs to mature chondroid cells and revealing a mechanism of cell destabilization in the late stage.

The AO/EB assay is applicable for ZnO nanoparticles according to their cell membrane destabilization potential.

Our study supports the notion that exposure to ammonia results in cell membrane destabilization, potentially affecting membrane permeability, enhancing uptake and thus synergistic effects of multiple-contaminant exposure.

In a number of in vitro studies, certain HDPs have been shown to be cytotoxic to tumor cells either directly through cancer cell membrane destabilization and lysis or through the initiation of apoptosis in the cancer cell.

Moreover, the modification with aptamer and HA2 (GS-PEG/HA2-Apt) could enhance the cellular uptake by 15 73 % in comparison with GS-PEG-Apt, which is due to the fact that induced HA2 peptide mediates cell membrane destabilization, further enhancing endosomal escape and increasing cellular distribution [28].

The novel engineered peptides encompass both the LPS-binding and aggregation-prone regions of parental ECP, providing the appropriate structural features for peptide attachment to the bacterial exopolysaccharide layer and bacterial cell membrane destabilization, thereby promoting biofilm removal at micro molar concentrations.

It seems unlikely that complete chemisorption and polysalt formation (eq 2) is required for pore formation and osmotic processes leading to cell membrane destabilization.

Other phenomena such as the loss of the function of transporters, ATPases and ion channels, deranged metabolism, cytoskeleton, and cell polarity destabilization with loss of cell membrane integrity are present.

This result suggests exploring the extent of polycation chemisorption in conjunction with kill kinetics to better understand polysalt formation described by eq 2 and the relationship to pore formation and osmotic processes leading to cell membrane destabilization due to stress.

All of these second stimuli share the ability to subvert the homeostasis of the cell by destabilization of lysosomes and mitochondria or by perturbation of the plasma membrane [[ 7],[ 8]].

Knockdown of LEDGF in cancer cells induces destabilization of lysosomal membranes and cathepsin-mediated cell death, while ectopic expression stabilizes lysosomes and prevents cancer cell death.