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Thus, the cell cycle phase distribution per cycling cells would reflect the biology of cancers.
DSB repair pathway choice is influenced by a number of factors including cell cycle phase.
We developed fluorescent reporters to quantify DSBs, HR and cell cycle phase in individual, living cells.
This group of genes shares predicted roles in "mesenchymal cell differentiation", "mitotic cell cycle phase transition", and "tube morphogenesis".
Bottom, FACS analysis of cell cycle phases in synchronized PSFs (left) and RT qPCR analysis of mRNA levels of cell cycle phase markers (right).
The sorted G1 and out-of-G1 cell cycle phase populations were then characterized for their H3K9me2 status (Figs 2f and S3).
(b) All single cells (n = 455) ordered by mean methylation (based on single cell RRBS) and colored by sorted cell cycle phase.
The data indicated the successful establishment of cell lines expressing G9a restricted to the G1 or late G1-M cell cycle phase.
Cell cycle phase was detected using a flow cytometer (FACS420, BD Biosciences, San Jose, CA).
The sensitivity and consequent biological effects of radiation exposure are dependent on the cell cycle phase.
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Cell cycle-specific, cell cycle-non specific, cell cycle phase-specific and cell cycle phase-non specific drugs can be simulated, as detailed in [23].
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