Sentence examples for cell cycle elements from inspiring English sources

Both in vitro and in vivo evidences for involvement of cell cycle elements in stroke was reported in a previous study [ 31].

The CDK inhibitors flavopiridol and olomoucine also protected the neurons from these conditions, suggesting that these cell cycle elements might mediate death signalling as a result of DNA-damaging environments [ 4].

Taken together, these data provided support that the cell cycle regulatory elements are truly functional in the context of an oncolytic HSV-1.

Among them, we paid more attention to one SNP −31 G/C (rs9904341) in the promoter of survivin located at the cell cycle dependent elements (CDE) and cell cycle homology regions (CHR) repressor binding site [ 44].

This system appears to be based upon reciprocal activation of intracellular signaling cascades involving secreted factors and their receptors, ion channels, transporters, protein kinases and phosphatases, transcription factors, and cell cycle control elements.

However, the same cells have been reported not to express p16INK4a mRNA or protein (Inoue et al, 2004), suggesting that the substitution of the ICP6 sequence with the cell cycle regulatory elements may be functioning differently from the ICP6 deleted mutant HSV-1 mutant virus.

These cell cycle regulatory elements have facilitated the ability of YE-PC8 viruses to mediate transgene expression in accordance with the proliferation status of the host cells, but this was not observed in matched control virus where the luciferase reporter gene was placed under the regulation of the ubiquitous CMV promoter.

Taken together, these results confirmed that transgene expression mediated by YE-PC8 was regulated by the cell cycle-regulatory elements.

Additionally, Aβ-mediated cell death, at least in vitro, is dependent on the presence of various cell cycle-related elements [ 62].

This difference in digestion pattern between pYEbacPC8 and parental pYEbac102 was due to the substitution of the ICP6 sequence with the cell cycle-regulatory elements.

Using BAC recombineering, the ICP6 gene was successfully replaced with similar cell cycle-regulatory elements as in previous studies (Ho et al, 2004).