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We found that the macrophage-fibroblast cell circuit is stable and robust to perturbations.
These findings illustrate principles of cell circuit design and provide a quantitative perspective on cell interactions.
A $32.5 million grant will launch the Klarman Cell Observatory at the Broad Institute, which will foster groundbreaking discoveries and technological advances in cell circuit research.
Here, we engineer a combinatorially activated T cell circuit in which a synthetic Notch receptor for one antigen induces the expression of a CAR for a second antigen.
Both normal and triode operation were found to lead to self-sustained current and potential oscillations in the fuel cell circuit over wide ranges of external resistive load.
It is shown that the application of electrolytic potential between the cathode and an auxiliary electrode can affect the performance of the fuel cell circuit in a controllable and reversible manner.
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MIT News article on "Cell circuits remember their history", February 2013.
Cell circuits: Scientists will use the Fluidigm chip (above) to analyze tumor cells isolated from the blood of patients with prostate cancer.
The simulations illustrate two typical Mitral-Granule cell circuits in the olfactory bulb of vertebrates: distance-independent lateral inhibition and gating effects.
Model files for the entry "Olfactory Computations in Mitral-Granule Cell Circuits" of the Springer Encyclopedia of Computational Neuroscience by Michele Migliore and Tom Mctavish.
A parallel SER (soft error rate) evaluation framework ASSET-VLG was developed to analyze the SER of both combinational and sequential standard cell circuits.
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