Sentence examples for cell chaperones from inspiring English sources
In the crowded cell, chaperones help prevent partly folded proteins from bumping into other proteins that may try to swap elements or otherwise interfere with proper folding.
Thus, the use of T cell chaperones for AuNP delivery could enhance the efficacy of nanoparticle-based therapies and imaging applications by increasing AuNP tumor accumulation.
Overproduction of soluble recombinant protein in E. coli can be limited by the deprivation of host cell chaperones that are required for correct folding of the respective protein.
Once inside the cell, chaperones, such as UreG and HypAB, bind and insert nickel into the appropriate protein (e.g. urease) [ 76].
Cell chaperones which assist in normal protein folding and removal of misfolded proteins may pose promising therapeutic targets in ILD [ 27].
There are significant challenges as the pore size of the B-domain requires unfolding of proteins in order to translocate followed by refolding of the protein which requires a host cell chaperone.
In cells, chaperones likely also function to clear aggregated species via chaperone-assisted autophagy or by proteasomal trafficking and degradation.
Proteins can interact with biological surfaces such as cell membrane, chaperones, cornea, bone, arteries, veins, and heart cavities of the cardiovascular system and also with non-biological surfaces including dialysis membranes and tubing, catheters, invasive surgical instruments, needles, and artificial implants.
The canonical pathways described in Table 1 are not amongst the top biofunctional categories, although heat shock and dnaj genes are prominent in both, again arguing that the host cell induces chaperones in response to infection.
In response to cell stress, chaperones prevent and reverse protein aggregation and ameliorate refolding.
Although differing only by five amino acids, these two histone H3 proteins are distinct in terms of expression during the cell cycle, chaperones for incorporation in the nucleosomes, localisation on the genome and presumably physiological functions [ 23, 54].
