Sentence examples for cell breadth from inspiring English sources

Post-Step trial suggestions emphasize the potential benefit of strategies that would improve T cell breadth [1].

Levels of selective constraint acting on a gene are affected by a number of factors, including gene expression level (measured, for instance, as the number or concentration of transcripts in the cell) and breadth (the number of tissues in which a gene is expressed) [ 7, 50- 52], codon bias [ 51, 53], connectivity of the encoded proteins [ 14- 16], and the number of paralogs [ 54, 55].

Comparisons between infected cases and non-infected matched controls among Step Study vaccine recipients showed no significant differences in terms of HIV-specific T-cell IFN-γ, IL-2, and TNF-α responses by T-cell subset, breadth, magnitude, or polyfunctional profile [2].

For these cells, the breadth of application will depend largely on the extent of the scientific imagination.

Interestingly, mice primed with full-length gag and boosted with DNA vaccine fragments induced similar T-cell response breadth as mice both primed and boosted by fragments DNA.

Parameters of interest when assessing a vaccine-induced HCV-specific T-cell population include breadth, cytokine production, cytolytic capacity, magnitude, phenotype and proliferative capacity.

To support effective host defense, the T cell repertoire must balance breadth of recognition with sensitivity for antigen.

Some gene therapy strategies are compromised by the levels of gene expression required for therapeutic benefit, and also by the breadth of cell types that require correction.

Summarized clinical and virological data including HIV-1 clade, viremia, CD4+ T cell counts, therapy and breadth of neutralization are shown in Table S1.

Mice displayed CD4+ and CD8+ T cell responses of significant breadth and magnitude, and 16 out of the 18 encoded epitopes were recognized.

Our strategy does not screen for antibodies against known antigens or evaluate antibodies secreted or sequestered in the serum at discrete times, but rather uniquely, the aim here is to monitor tumor cell-reactive IgG antibodies produced by B cell cultures, elucidating the breadth of the long-term mature B cell repertoire recognizing melanoma antigens expressed on the surface of cancer cells.