Sentence examples for cell based immune response from inspiring English sources

The outcome of a particular T cell based immune response is likely to be determined by the balance between the effector and regulatory T cell pools.

HIV may be acting as an indirect co-factor in the etiology of Burkitt lymphoma by reducing the effectiveness of T cell based immune response to oncogenic viruses [28] or by reducing the EBV-specific T cell function, leading to proliferation of EBV infected B cells and eventual tumor formation [29].

Researchers have demonstrated that both T and B cell based immune responses are generated against tumors., The presence of lymphocytes in a tumor is associated with a better patient outcome.

To determine if the increased protection after B7.1-expressing tumor immunization was mediated by a T-cell based immune response, we used mAbs to deplete CD8+ or CD4+ T cells in C57BL/6 mice before immunization and tumor cell challenge.

Thus, expression of both genes in tumor cells can facilitate the induction phase of the T-cell based immune response.

Ad serotype 5 has been the most widely used Ad vector because of earlier, historical development, its important safety profile and its remarkable capacity to induce strong, long-lasting and broad T-cell based immune responses, in particular CD8+ driven ones [ 2].

Here we discuss various conditions, which are important during generation and administration of dendritic cells to elicit a tumouricidal T cell-based immune response.

The biggest success of immunological bioinformatics is the development of algorithms for prediction of peptide binding affinity to the human leukocyte antigen (HLA) - one of the rate limiting steps in T cell-based immune response [ 9].

As their CD4+T-cell-based immune response is attenuated, HIV-infected patients are often coinfected with hepatitis B virus (HBV) or hepatitis C virus (HCV), which, in addition to the hepatotoxicity of ART, leads to the development of liver cirrhosis and failure.

DC-SIGNR plays a role in cell adhesion, cell signaling, primary immune response and pathogen internalization45.

Our data suggest human Brucella vaccine candidates need to utilize correlates of protection that are based on the cell-mediated immune response, as the vaccine caused an increase in serological measurements, but was observed to be ineffective.