Sentence examples for cell based bioassay from inspiring English sources
A significant number of patients (n= 9, 60%) developed GM-CSF antibodies which neutralized the biological activity of GM-CSF in vitro in a cell-line based bioassay.
In the present study, we developed a new mass spectrometry based bioassay for this purpose.
This potato based bioassay was employed since a comparable gnotobiotic tissue culture system had not yet been developed for maize.
With the cell based IGF-IR bioassay at hand we are able to determine the ability of serum to activate the IGF-IR in vitro[ 16].
This implies that for every target ligand interaction, the optimum bioassay conditions for on-line MS based bioassays have to be determined.
Moreover, compared to binding assay, cell-based bioassay could detect the impact of chemical modifications, such as deamidation in the complementarity-determining region or the Fc region of the molecule on its potency.
Thorough understanding of how to control cell behaviors including cell adhesion, orientation, migration and differentiation on an artificial surface is critical in materials and life sciences such as advanced biomedical engineering, tissue engineering, and cell-based bioassay.
With the goal of developing a cell-based bioassay that is highly optimized for sensitivity, specificity, precision, and robustness, we performed 2 DOE experiments for assay optimization and 1 DOE experiment to validate assay robustness.
Biological activity of the stressed preparations was assessed in three different in vitro cell-based bioassay systems: a late-stage anti-proliferative assay and early-stage assays measuring reporter gene activation or endogenous gene expression by quantitative real time Reverse Transcription-Polymerase Chain Reaction (qRT-PCR).
Hisako Ishige and Hiroshi Kohriki performed the cell-based bioassay.
