Sentence examples similar to cell based aggregation from inspiring English sources

A likely explanation is that the T cell based read-out, with aggregation of pMHCII/TCR in immunological synapses, is rather more sensitive than binding of soluble TCRs as detected in flow cytometry.

The impact of caspase cleavage was confirmed in a cell based model, showing that predominantly caspase-1-mediated fragmentation of expanded ataxin-3 resulted in increased aggregation and treatment with caspase inhibitors prevented inclusion formation in vitro [ 61].

Because all germ cells in the perinatal rat testis immunostain intensely for VASA in the cytoplasm, we were able to use VASA immunohistochemistry to develop an objective method for measuring germ cell aggregation, based on average germ cell cluster size, in testes from control and DBP-exposed rats at E17.5, E21.5, and PND4.

Subsequently, based on the partitioned cells and equivalent color classes, we propose a Cell-based Aggregation Scheduling (CAS) algorithm for the SDA problem in probabilistic WSNs.

A cell-based aggregation assay demonstrates that W32S substitution significantly mitigates inclusion formation.

To evaluate this property, we developed a quantitative cell-based aggregation (CBA) seeding assay.

By using cell-based aggregation assays, we identified several novel variants of SOD1G93A with reduced aggregation propensity within mammalian cells.

Since S32 substitution decreased the inclusion formation of multiple mutants including G93A and G85R, and as the obligate misfolded monomer G85R is a promiscuous acceptor of seed-induced SOD1 aggregation11,34, we focused our quantitative time-lapse cell-based aggregation studies on the pathogenic G85R mutant.

We have previously developed a cell-based aggregation model by cloning in-tandem 12 copies of the Q/N region from TDP-43 in the C-terminal of EGFP, resulting in the expression of a so-called EGFP-12xQ/N protein (16).

Ghosh, D. et al. Structure based aggregation studies reveal the presence of helix-rich intermediate during α-Synuclein aggregation.

Considering the presence of CD44 ligand hyaluronan, which enhanced cell aggregation, and the presence of E-cadherin, which mediated cell-cell interaction, we presented a model of cell-matrix-cell interaction based on the observation of the two groups of cell mixture (Figure 6B).