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In order to improve cells infiltration into the fibers network, direct electrospinning of a 3D aligned nanofibrous tube has been realized, promoting cell alignment and myotube formation [101].
The nanofilm creates a flexible support for cell contraction and the aligned PIEZO microfibers deposited on top of the nanofilm creates conditions for cell alignment and electrical stimulation of the seeded cells.
The composite scaffolds exhibited good biocompatibility and facilitated cell alignment and proliferation in vitro.
Fb-free MP films were not effective in cell alignment, and clumps were formed.
3D micropatterned scaffolds can promote cell alignment and muscle tissue formation.
Histological analysis 6 weeks postoperatively showed no fibrosis or encapsulation but instead longitudinal cell alignment and axonal regrowth.
Similar(12)
Mjd siRNA depletion in C2C12 cells was shown to induce morphological alterations (round shape), defects in cell-cell alignment, and fragmented myosin-positive filements.
The up-regulation found for CD248 or Endosialin, known as a potential actor of angiogenesis in which it contributes to cell-cell alignment and contacts [ 24], seems to be explained.
It did for one of the proteins called cadherins, which are found throughout the animal kingdom and are apparently involved in cell alignment, adhesion and signaling.
To preserve cell alignment ability and improve biocompatibility, the stability of patterned alginate fibers was adjusted by regulating the level of ion crosslinking.
For example, nanoscaffolds, including nanoscale-structured or nanoscale surface-modified vascular scaffolds, can influence cell alignment, adhesion, and differentiation to promote better endothelization.
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